Seminars in Ultrasound, CT and MRI
Volume 30, Issue 4 , Pages 352-358 , August 2009

Management of Small Renal Masses

  • David A. Kunkle, MD

      Affiliations

    • Carolina Urological Associates, Winston-Salem, NC
    • Corresponding Author InformationAddress reprint requests to David A. Kunkle, MD, Carolina Urological Associates, 140 Kimel Park Drive, Winston-Salem, NC 27103
  • ,
  • Alexander Kutikov, MD

      Affiliations

    • Department of Urologic Oncology, Fox Chase Cancer Center, Philadelphia, PA
  • ,
  • Robert G. Uzzo, MD

      Affiliations

    • Department of Urologic Oncology, Fox Chase Cancer Center, Philadelphia, PA

References 

  1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin. 2008;58:71–96
  2. Chawla SN, Crispen PL, Hanlon AL, et al. The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature. J Urol. 2006;175:425–431
  3. Jayson M, Sanders H. Increased incidence of serendipitously discovered renal cell carcinoma. Urology. 1998;51:203–205
  4. Volpe A, Panzarella T, Rendon RA, et al. The natural history of incidentally detected small renal masses. Cancer. 2004;100:738–745
  5. Hollingsworth JM, Miller DC, Daignault S, et al. Rising incidence of small renal masses: A need to reassess treatment effect. J Natl Cancer Inst. 2006;98:1331–1334
  6. Kunkle DA, Haas NB, Uzzo RG. Adjuvant therapy for high-risk renal cell carcinoma patients. Curr Urol Rep. 2007;8:19–30
  7. Frank I, Blute ML, Leibovich BC, et al. Independent validation of the 2002 American Joint Committee on cancer primary tumor classification for renal cell carcinoma using a large, single institution cohort. J Urol. 2005;173:1889–1892
  8. Hafez KS, Fergany AF, Novick AC. Nephron sparing surgery for localized renal cell carcinoma: Impact of tumor size on patient survival, tumor recurrence and TNM staging. J Urol. 1999;162:1930–1933
  9. Moinzadeh A, Gill IS, Finelli A, et al. Laparoscopic partial nephrectomy: 3-year follow up. J Urol. 2006;175:459–462
  10. Aron M, Gill IS. Minimally invasive nephron-sparing surgery (MINSS) for renal tumours (Part II: Probe ablative therapy). Eur Urol. 2007;51:348–357
  11. Mahnken AH, Gunther RW, Tacke J. Radiofrequency ablation of renal tumors. Eur Radiol. 2004;14:1449–1455
  12. Negrier S, Escudier B, Lasset C, et al. Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma (Groupe Français d'Immunotherapie). N Engl J Med. 1998;338:1272–1278
  13. Kunkle DA, Chen DY, Greenberg RE, et al. Metastatic progression of enhancing renal masses under active surveillance is associated with rapid interval growth of the primary tumor. [abstract] J Urol. 2008;179:1089
  14. Kunkle DA, Crispen PL, Chen DY, et al. Enhancing renal masses with zero net growth during active surveillance. J Urol. 2007;177:849–854
  15. Abouassaly R, Lane BR, Novick AC. Active surveillance of renal masses in elderly patients. J Urol. 2008;180:505–508discussion 508-509
  16. Crispen PL, Viterbo R, Fox EB, et al. Delayed intervention of sporadic renal masses undergoing active surveillance. Cancer. 2008;112:1051–1057
  17. Stec AA, Coons BJ, Chang SS, et al. Waiting time from initial urological consultation to nephrectomy for renal cell carcinoma—Does it affect survival?. J Urol. 2008;179:2152–2157
  18. Uchida M, Imaide Y, Sugimoto K, et al. Percutaneous cryosurgery for renal tumours. Br J Urol. 1995;75:132–136
  19. Hoffmann NE, Bischof JC. The cryobiology of cryosurgical injury. Urology. 2002;60:40–49
  20. Gill IS, Novick AC. Renal cryosurgery. Urology. 1999;54:215–219
  21. Onik GM, Reyes G, Cohen JK, et al. Ultrasound characteristics of renal cryosurgery. Urology. 1993;42:212–215
  22. Kunkle DA, Uzzo RG. Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis. Cancer. 2008;113:2671–2680
  23. Zlotta AR, Wildschutz T, Raviv G, et al. Radiofrequency interstitial tumor ablation (rita) is a possible new modality for treatment of renal cancer: Ex vivo and in vivo experience. J Endourol. 1997;11:251–258
  24. McGovern FJ, Wood BJ, Goldberg SN, et al. Radio frequency ablation of renal cell carcinoma via image guided needle electrodes. J Urol. 1999;161:599–600
  25. Goldberg SN, Gazelle GS, Mueller PR. Thermal ablation therapy for focal malignancy: A unified approach to underlying principles, techniques, and diagnostic imaging guidance. AJR Am J Roentgenol. 2000;174:323–331
  26. Zagoria RJ, Hawkins AD, Clark PE, et al. Percutaneous CT-guided radiofrequency ablation of renal neoplasms: Factors influencing success. AJR Am J Roentgenol. 2004;183:201–207
  27. Matin SF, Ahrar K, Cadeddu JA, et al. Residual and recurrent disease following renal energy ablative therapy: A multi-institutional study. J Urol. 2006;176:1973–1977
  28. Goldberg SN, Grassi CJ, Cardella JF, et al. Image-guided tumor ablation: Standardization of terminology and reporting criteria. Radiology. 2005;235:728–739
  29. Campbell SC, Novick AC, Herts B, et al. Prospective evaluation of fine needle aspiration of small, solid renal masses: Accuracy and morbidity. Urology. 1997;50:25–29
  30. Weight CJ, Kaouk JH, Hegarty NJ, et al. Correlation of radiographic imaging and histopathology following cryoablation and radio frequency ablation for renal tumors. J Urol. 2008;179:1277–1281
  31. Gill IS, Remer EM, Hasan WA, et al. Renal cryoablation: Outcome at 3 years. J Urol. 2005;173:1903–1907
  32. Cadeddu JA. Re: Correlation of radiographic imaging and histopathology following cryoablation and radio frequency ablation for renal tumors. Weight JW, Kaouk JH, Hegarty NJ, et al J Urol. 2008;179:1277–1283
  33. Raman JD, Stern JM, Zeltser I, et al. Absence of viable renal carcinoma in biopsies performed more than 1 year following radio frequency ablation confirms reliability of axial imaging. J Urol. 2008;179:2142–2145
  34. Shingleton WB, Sewell PE. Cryoablation of renal tumours in patients with solitary kidneys. BJU Int. 2003;92:237–239
  35. Raman JD, Thomas J, Lucas SM, et al. Radiofrequency ablation for T1a tumors in a solitary kidney: Promising intermediate oncologic and renal function outcomes. Can J Urol. 2008;15:3980–3985
  36. Jacobsohn KM, Ahrar K, Wood CG, et al. Is radiofrequency ablation safe for solitary kidneys?. Urology. 2007;69:819–823discussion 823
  37. Hegarty NJ, Gill IS, Desai MM, et al. Probe-ablative nephron-sparing surgery: Cryoablation versus radiofrequency ablation. Urology. 2006;68:7–13
  38. Kunkle DA, Uzzo RG. Significant differences exist in reporting for ablation of renal masses: A comparison of studies published in urology and radiology literature. [abstract] J Urol. 2008;179:403
  39. Atwell TD, Farrell MA, Callstrom MR, et al. Percutaneous cryoablation of 40 solid renal tumors with US guidance and CT monitoring: Initial experience. Radiology. 2007;243:276–283
  40. Bandi G, Wen CC, Hedican SP, et al. Cryoablation of small renal masses: Assessment of the outcome at one institution. BJU Int. 2007;100:798–801
  41. Finley DS, Beck S, Box G, et al. Percutaneous and laparoscopic cryoablation of small renal masses. J Urol. 2008;180:492–498discussion:498
  42. Bandi G, Hedican S, Moon T, et al. Comparison of postoperative pain, convalescence, and patient satisfaction after laparoscopic and percutaneous ablation of small renal masses. J Endourol. 2008;22:963–967
  43. Badwan K, Maxwell K, Venkatesh R, et al. Comparison of laparoscopic and percutaneous cryoablation of renal tumors: A cost analysis. J Endourol. 2008;22:1275–1277
  44. Klingler HC. Kidney cancer: Energy ablation. Curr Opin Urol. 2007;17:322–326
  45. Kunkle DA, Egleston BL, Uzzo RG. Excise, ablate or observe: The small renal mass dilemma—A meta-analysis and review. J Urol. 2008;179:1227–1233

PII: S0887-2171(09)00020-1

doi: 10.1053/j.sult.2009.03.002

Seminars in Ultrasound, CT and MRI
Volume 30, Issue 4 , Pages 352-358 , August 2009